18 Sep 2017 --- Researchers have found an explanation for why cutting calorie intake could dramatically extend lifespan in certain animal species. In work published online in Nature Communications, investigators at the Lewis Katz School of Medicine at Temple University (LKSOM) in Philadelphia, US, are the first to show that the speed at which the epigenome changes with age is associated with lifespan across species and that calorie restriction slows this process of change, potentially explaining its effects on longevity.