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Radicle Science CEO unpacks 20-arm Holobiome prebiotic trial for mental wellness

Radicle Science and Holobiome have opened enrollment for a two-year research initiative, Gut-Feelings, to identify prebiotics for mental wellness and build a new model of the gut microbiome. In a randomized, decentralized trial, more than 6,000 people will test 19 prebiotic interventions against a placebo simultaneously to determine which ones can improve feelings of anxiety and in which populations. Initial results are expected in the second half of 2027. 
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Next-gen supplements pair precision nutrition with consumer-friendly formats
The next generation of supplements is moving beyond traditional formats and one-size-fits-all solutions toward science-backed nutrition in simpler, more enjoyable formats. Manufacturers spot opportunities in targeted solutions, personalized healthy aging, metabolic health, and functional food and beverages. Nutrition Insight speaks with Sirio, ADM, Gelita, Lubrizol, Concordix, and Ourvita to explore how evolving consumer expectations are driving supplement innovations. They also underscore the importance of balancing ingredient efficacy and clinically relevant doses with convenience and sensory appeal. 
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Nitrosamine risk could become focus for nutraceuticals, says LabAnalysis’ Sharad Vora
Consumers increasingly expect nutraceuticals to deliver high levels of quality, consistency, and safety, a shift that may push manufacturers toward more sophisticated testing strategies, according to Sharad Vora, sales manager UK and Nordics at LabAnalysis Life Science. When a company develops a new vitamin, protein supplement, or other nutraceutical, it must evaluate purity, impurity profiles, stability, and batch-to-batch consistency, Vora tells Nutrition Insight.
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Beyond Longevity: The science behind healthier aging
Discover how science-backed nutrition is shaping the future of longevity and healthspan. Stratum Nutrition’s latest white paper explores clinically studied ingredients supporting mobility, cognitive function, skin health, digestive wellness, and more, highlighting innovative formulation opportunities to help consumers age healthier and live better.

This Technical Paper is brought to you by Stratum Nutrition.
SupplySide Global 2026 Wecare Probiotics video thumbnail: A representative showcases a BC99 probiotic product at the WECARE Probiotics exhibition booth while attendees discuss products at a trade show.
SupplySide Global 2026: Wecare Probiotics scales up production and launches CDMO services

Dr. George Zhou, director of applied technology at Wecare Probiotics, introduced the company’s new client services in research and contract development and manufacturing (CDMO), supporting customers with clinical studies and regulatory solutions for probiotic strains. He shared clinical research on gummies with Wecare Probiotics’ Weizmannia coagulans BC99 strain, showing benefits for immunity in adults and children. Zhou also highlighted the company’s latest facility expansion, which adds 500 metric tons of probiotic production capacity annually.

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Fi Europe 2026 preview: Health, taste and affordability drive ingredient innovation
From clear protein drinks and prebiotic fibers to natural colors and sugar reduction, Fi Europe 2026 in Frankfurt, Germany (Nov 17–19), will showcase ingredients addressing manufacturers’ biggest (re)formulation challenges. Our preview explores what some of the world’s most innovative suppliers are bringing to the show, highlighting concepts and technologies designed to balance taste, texture, nutrition, sustainability, and cost, alongside opportunities across functional beverages, healthy snacks, dairy alternatives, and more.  
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UK is running out of time on healthy food reforms, warn 68 health groups
alarm clock next to bowl of cereal, glass of juice, and measuring tape
Sixty-eight health organizations and experts are urging the UK government to speed up food policy reforms to target obesity and improve public health, warning that the government is running out of time to deliver promised healthy food reforms.
21st.Bio files EU Novel Food application for precision-fermented...
Thomas Schmidt CEO of 21st.Bio
21st.Bio has filed an EU Novel Food application for BLG Essential+, its bovine milk protein beta-lactoglobulin (BLG) derived from precision fermentation. According to the Danish biotech company, the product is less resource intensive than traditional dairy, which could help address supply constraints in the European whey protein market. The application, submitted to the European Commission for safety assessment by the European Food Safety Authority, follows the US FDA’s “no questions” response to the company’s generally recognized as safe (GRAS) notice in October 2025. 21st.Bio had self-affirmed the ingredient’s GRAS status in September 2024.
Nestlé launches plant-based Compleat Bolus Blends to simplify tube feeding
Nestlé Compleat Bolus Blends
Nestlé has expanded its medical nutrition portfolio with Compleat Bolus Blends. The nutritionally complete, plant-based product range was developed to simplify bolus tube feeding for patients, caregivers, and health care professionals.  Nestlé says that Compleat Bolus Blends is launching across Europe between November 2026 and early 2027, starting in Germany, Austria, Benelux, Italy, the Nordic countries, and the UK. It adds that future launches are planned in the Middle East, Australia, and Türkiye.
Kēpos launches 300-person trial of HMOs and human lactoferrin for adult...
Kēpos for Digestion
Supplement brand Kēpos has launched a randomized, placebo-controlled clinical trial evaluating the effectiveness of its flagship Kēpos for Digestion product for adults experiencing digestive discomfort. The new study will explore how the formula’s human milk bioactives — best known from infant formula — can support adult gut health.
Purina Pro Plan Veterinary launches cat joint and hairball supplements, urinary...
Cat at the vet
In the US, Nestlé’s Purina Pro Plan Veterinary has launched two new cat nutrition supplements for mobility and hairball management, with a third product — a therapeutic urinary diet — scheduled to follow on November 23. While Purina shares key ingredient details for the available supplements, it has yet to disclose the full formulation for the upcoming diet. These additions expand the brand’s Pro Plan Veterinary feline portfolio, which includes therapeutic diets and supplements to support hydration, digestive health, calm behavior, and other essential aspects of cat care.
Pilot to profit: How can Europe close its alternative protein scale-up gap?
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Food Ingredients First

Alternative protein innovation in Europe is proliferating, but manufacturers sometimes still struggle with moving from promising laboratory processes into reliable and cost-effective production. At Future of Protein Production (FPP) Amsterdam 2026, industry discussions centered around how process engineering, shared infrastructure, and commercial discipline can help innovators cross the scale-up gap. According to the Good Food Institute Europe, European funders invested €1.3 billion (US$1.4 billion) in alternative-protein research between 2020 and 2025. However, the findings from a European Commission-funded study underscore the challenges facing innovators seeking to move beyond research and pilot production. High production costs, uneven technological readiness, and regulatory uncertainty are limiting biomass and precision fermentation in the EU. 
Highlighted features
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Nutrition & Health News
Webinar preview: Morinaga Milk unpacks bifidobacteria’s...
Morinaga Milk’s upcoming webinar will examine what bifidobacteria may mean for healthy aging beyond the gut. The free webinar, “Bifidobacteria and Healthy Aging: New Insights into Aging and Immunity,”  takes place on November 19 at 15:00 CET (14:00 UTC) and is open for registration.
US Capitol building
Nutrition & Health News
US industry and advocates split on GRAS reform as Democrats...
Democrats’ win in the US House of Representatives and the Senate in the November 3 midterm elections could shape the nutrition and health agenda over the next two years. Democrats will take control of both chambers in January 2027, chairing committees that oversee the FDA.
Making a protein drink
New Product Development
Fi Europe 2026: Cosun Ingredients targets GLP-1 and gut...
At the upcoming Food Ingredients (Fi) Europe 2026 trade show (Nov 17–19), Cosun Ingredients will display new food concepts that bring its portfolio of protein, fibers, prebiotics, and texture solutions to life. The company notes these concepts meet consumer demands and trends in multifunctional products, gut health, protein, and GLP-1 companion nutrition. Margriet van Gurp, manager of application and technical sales at Cosun Ingredients, tells Nutrition Insight that visitors can sample a wide range of concepts at the event in Frankfurt, Germany. 

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Gut-brain synergy in focusNov2026

Innova Market Insights data shows that consumers increasingly recognise gut health benefits beyond digestion, particularly its links to mental well-being, energy and sleep. Global food, drink and supp...

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Product innovation

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Next-gen supplements Nov 2026

Innova Market Insights data indicates that the supplement category grew at a 2% CAGR from October 2021 to September 2026. Vitamins & minerals were the leading subcategory for supplement launches, accounting for 27% of launches from October 2025 to September 2026. Dietary fiber and antioxidant subcategories had the biggest increase in launches.

Trend analysis

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Brain health supplement boostersNov 2026

Innova Market Insights data indicates that concentration and focus are top of mind for consumers. Brands are responding by increasing brain health supplement launches. Europe leads brain health supplement launches at 45%, followed by North America at 32%. Vitamins and minerals are the leading subcategory at 31%, capsules are the top format at 33%, and citicoline emerges as an ingredient with great potential for innovation.

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SupplySide Global 2026 Wecare Probiotics video thumbnail: A representative showcases a BC99 probiotic product at the WECARE Probiotics exhibition booth while attendees discuss products at a trade show.
Video06:31
SupplySide Global 2026: Wecare Probiotics scales up production and launches CDMO services

Dr. George Zhou, director of applied technology at Wecare Probiotics, introduced the company’s new client services in research and contract development and manufacturing (CDMO), supporting customers with clinical studies and regulatory solutions for probiotic strains. He shared clinical research...

Dr. Andrew Ross, Rousselot
Video09:18
SupplySide Global 2026: Rousselot launches Nextida NxCogni for cognitive clarity
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Webinars44:10
Magnesium bisglycinate in focus: why full chelation matters
Julie Imperato and Leslie Lannebere, Nexira
Video08:59
SupplySide Global 2026: Nexira spotlights women’s health, sports performance & GLP-1 nutrition
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