14 Feb 2019 --- Researchers have established a correlation between depression and a group of neurotransmitter-producing bacteria found in the human gut, further expanding clinical evidence of the gut-brain axis. Interestingly, an inverse relationship between specific gut bacteria and brain activity in areas connected to depression were identified in the animal study. Published in Nature Microbiology, the findings could lead to the development of bacterial therapeutics for depression, including a growing role for probiotics, but significant work is first required, the researchers note.