30 Oct 2019 --- Spain-based Pharmactive Biotech has optimized the quality and concentration of its saffron (Crocus sativus L.) extract, affron, with a natural proprietary extraction process called AFF ON Cool-Tech. The new technology maintains the traditional Mediterranean botanical’s freshness and purity while improving the value of the clean-label product. This process is gentle on the plant to ensure its active compounds remain potent. Pharmactive’s Affron is touted as helping with relaxation, mental and physical balance and maintaining a positive mood.