02 Nov 2017 --- The human skeleton is much more than the structure supporting muscles and other tissues. It produces hormones, including osteocalcin, which affects how we metabolize sugar and fat. In a recent paper in The Journal of Clinical Investigation, Mathieu Ferron, Professor at Université de Montréal’s Faculty of Medicine, and his team have unveiled a new piece of the puzzle that explains how osteocalcin works. The discovery may someday open the door to new ways of preventing type 2 diabetes and obesity.