11 March 2014 --- A short-term study has found that oral glucosamine supplementation is not associated with a lessening of knee cartilage deterioration among individuals with chronic knee pain. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR) journal, indicate that glucosamine does not decrease pain or improve knee bone marrow lesions - more commonly known as bone bruises and thought to be a source of pain in those with osteoarthritis (OA).