29 Nov 2023 --- Researchers suggest that reducing the intake of the amino acid isoleucine extends the lifespan of mice, making them leaner and less frail as they age and reducing cancer and prostate problems. They are optimistic that these results can be translated to humans, but further research is required. Mice consuming a reduced isoleucine diet lived longer, by an average of 33% for males and 7% for females. Based on 26 health measurements, these mice were in much better shape during their extended lives.