09 Jun 2020 --- Research is continuing to shed light on factors that may cause people to gain or lose weight. UK researchers from the University of Warwick found that cells in the brain called tanycytes increase appetite when stimulated by light. Meanwhile, scientists from Virginia Tech, US, uncovered a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or raising body temperature. These breakthroughs could be early steps in exploring treatment pathways for obesity, which affects over 40 percent of US adults, and 13 percent of the global population.