23 Jan 2020 --- Following a Nestlé Research investigation into the factors that predispose children to develop Type 2 diabetes in adult life, new research has found that the earliest event leading to prediabetes is an early dysfunction of the beta-cell – the hormone that regulates blood sugar levels – independent of body weight. This is according to a first-of-its-kind study called EarlyBird also powered by the University of Plymouth in the UK, which sheds new light on the biological and physiological factors that are relevant for metabolic health in childhood. The study findings may help shape the way nutritional choices can target the insulin response to meals and the body’s ability to regulate blood sugar levels.