30 Nov 2017 --- The immune system plays a pivotal role in the amount of pain and disease progression experienced by patients with osteoarthritis (OA), researchers at McMaster University in Hamilton, Ontario, Canada have found. This discovery could lead to new strategies for improving joint pain management and immune function in the ever-increasing number of older adults with arthritis. In the US in particular, it has been suggested that the actual number of sufferers is much higher than current estimates.