02 Oct 2019 --- High levels of fructose in the diet inhibit the liver’s ability to metabolize fat properly. This is according to researchers at Joslin Diabetes Center in Boston, US, who also found that equally high levels of glucose in the diet actually improve the fat-burning function of the liver. This explains why high dietary fructose has more negative health impacts than glucose does, even though they have the same caloric content. The researchers now believe that a drug blocking fructose metabolism could prevent the negative actions of fructose. These actions include fatty liver disease and adverse metabolic consequences, such as impaired glucose tolerance and Type 1 diabetes.