30 Mar 2018 --- Just one high-fat milkshake can change healthy red blood cells into small, spiky cells that help set the perfect stage for cardiovascular disease, scientists report. Just four hours after consuming a milkshake made with whole milk, heavy whipping cream and ice cream, healthy young men had blood vessels less able to relax and an immune response similar to one provoked by an infection, the team of Medical College of Georgia scientists report in the journal Laboratory Investigation.