A new study published in the The Journal of Nutrition found that substituting two tablespoons of pure maple syrup for refined sugars reduced several cardiometabolic risk factors in humans. It was the first placebo-controlled clinical trial exploring potential health benefits of maple syrup in humans. “We know from decades of research that maple syrup is more than just sugar. It contains over 100 natural compounds, including polyphenols, that are known to prevent disease in part through their anti-inflammatory effects,” says Dr. André Marette, lead scientist on the study.