A recent clinical trial comparing 4:3 intermittent fasting to daily caloric restriction has revealed promising results for weight loss, according to a study published in Annals of Internal Medicine. The method involves eating normally for four days a week and significantly restricting calories on the other three non-consecutive days. Researchers from the University of Colorado School of Medicine, US, and their collaborators examined the effects of these two popular dietary interventions over 12 months among adults with overweight or obesity.