12 Nov 2019 --- A synergistic formula with a specific ratio of Maitake, Reishi and Shiitake mushroom extracts provides an increase in immune stimulation compared to the additive effect of the three individual extracts. This is according to an Integria Healthcare-sponsored study, now patented and published in PLOS ONE. This is the first report of a synergistic immune-modulating response in human macrophages elicited from a mushroom formula that is rationally derived from beta- and alpha-glucan content.
