16 Oct 2018 --- Obesity, insulin resistance and addictive life-style behaviors may be passed to future generations as a result of a high-fat maternal diet during, before and after pregnancy. A mice study, published in Translational Psychiatry, notes that the effects of the high-fat diet might even be passed on for three generations. This was the case although the original female mice never became obese and none of the following generations consumed a high-fat diet. The study highlights the strong potential for identifying underlying mechanisms that may be risk factors for people in developing obesity or addictions.