05 Jan 2024 --- While high-fat diets are linked to several diseases, such as diabetes, obesity and fatty liver disease, US-based researchers are now revealing how these diets affect genes. In their study, they connect high-fat diets to the dysregulation of genes involved in drug metabolism, epithelial barrier function — which regulates nutrient absorption and prevents the invasion of pathogenic bacteria — inflammatory bowel disease, colon cancer, the gut microbiome and COVID-19. The team from the University of California Riverside (UCR), US, fed mice diets with fat amounts close to the average fat consumption by US citizens at 40% of total calories.
