13 May 2016 --- New research shows that the heart health benefits of HDL, the 'good' cholesterol, may have been hyped-up. This new study shows, for the first time, that HDL's heart disease protection depends on the levels of two other blood fats (lipids) associated with heart disease. Scientists from the University of Maryland Medical Center say that if these fats are not within normal ranges, even a high HDL may not be protective.