10 Oct 2017 --- The onset of Type 1 diabetes is preceded by modification of MAIT lymphocytes, which are activated by intestinal flora, according to scientists from the Cochin Institute (CNRS/INSERM/Paris Descartes University) and their colleagues from AP-HP Necker-Enfants Malades Hospital in Paris. The MAIT lymphocyte cells – associated with mucosae and able to recognize elements of the microbiota – could, therefore, serve as new biomarkers for early detection and prevention of the illness. The researchers' findings are published in Nature Immunology.