08 Jul 2019 --- Researchers have discovered a method that reverses prediabetes in mice, and is likely to apply to humans as well. Scientist at the University of Utah Health found that deactivating an enzyme that shifts the position of two hydrogen atoms can reverse prediabetes. This provides valuable insight into how used new therapies could be developed for prediabetes, as well as other metabolic disorders such as diabetes and heart disease. The researchers have created a company, Centaurus Therapeutics, in order to develop drugs targeting the deactivated enzyme.