17 Jan 2019 --- Fasting intermittently (IF) may reprogram a variety of cellular responses and result in a range of health benefits, according to a US study conducted on mice. Fasting was found to affect circadian clocks in the liver and skeletal muscles, causing them to rewire their metabolism, which may promote health and protect from age-related diseases. The research, published in Cell Reports, opens new pathways of investigation that may lead to the development of nutritional strategies to improve health in humans.