30 Jan 2020 --- The spotlight is on low and no-calorie sweeteners ahead of the anticipated release of draft guidelines on the intake of non-sugar sweeteners from the World Health Organization (WHO) Nutrition Guidance Expert Advisory Group (NUGAG). A new report publicized by the International Sweeteners Association (ISA) argues that there is an extensive body of robust scientific evidence that shows that low and no-calorie sweeteners are safe and can be part of broader strategies to reduce sugar intake. However, this is still an area of controversy, with experts telling NutritionInsight how the microbiome is a particular potential point of concern.