19 Jul 2023 --- Psilocybin activates a different set of serotonin receptors rather than suppressing emotions which are common effects of antidepressants, according to a new study comparing the after effects of medical treatments and psilocybin. The researchers found that even though both are effective in treating depressive symptoms, they have different effects on the brain. Conventional antidepressants such as Selective Serotonin Reuptake Incubators (SSRIs) and psilocybin have therapeutic effects and act on the 5-HT systems. However, the study found that psilocybin acts as a direct agonist on some 5-HT receptors and confirmed that the magic mushroom compound often brings a higher acceptance of emotions.
