02 Mar 2020 --- A strain of Escherichia coli (E. coli) used in probiotic supplements, including Mutaflor’s offerings, has been linked to colorectal cancer mutations. While the Nissle 1917 strain has been hailed for human gut health, researchers from the the Hubrecht Institute (KNAW) and Princess Máxima Center in Utrecht, the Netherlands, argue the strain should now be critically re-evaluated in laboratories.