21 Dec 2017 --- Many individuals try to lose weight by dieting – but reduced-calorie diets are notoriously difficult to maintain. New research published in the Journal of Physiology indicates that lowering consumption of specific building blocks of proteins (amino acids) may combat the metabolic problems that occur in diabetes and obesity. In a mouse study, researchers at the University of Wisconsin-Madison found that lowering the consumption of specific types of amino acids called branched-chain amino acids (BCAAs) improved metabolic health, even when overall calories were not reduced.