09 Dec 2019 --- Probiotics and prebiotics may impact the microbiome of male infants differently to female infants, according to a study in 28-day-old piglets. A team of researchers from the Universities of Bristol and Reading in the UK found that the piglets produced very different levels of immune cells, antibodies and other immune-associated molecules depending on their sex. Gut health is pivotal for immunity and the female piglets reacted more favorably to the probiotic and prebiotic supplements. The findings could inform improved treatment for immunity disorders in infants that may need to be designed differently for girls and boys.