13 Jan 2023 --- Scientists in Portugal have pinpointed flavonoids and alkaloids as essential compounds behind coffee’s effects against non-alcoholic fatty liver disease (NAFLD), including in those with Type 2 diabetes. Researchers from the University of Coimbra write that coffee is well-known for “modest but significant” protection against NAFLD. NutritionInsight speaks with John Griffith Jones, co-author of the study, about the components of coffee’s impact on the liver and how the health benefits are explained.