02 Nov 2018 --- The gut microbiome has been linked to various aspects of human health, including obesity. Researchers at Walter Reed National Military Medical Center have now found that certain drugs, such as antibiotics, acid suppressants-histamine 2 receptor antagonists (H2RA) and proton pump inhibitors (PPIs), can alter the type and volume of bacteria in the gut. These medications, which are often over-prescribed in children, may have significant negative effects on health that were previously underappreciated, the researchers note.