25 Jun 2024 --- Researchers at Seraphina Therapeutics have discovered a nutritional deficiency syndrome — “the first in over 75 years” — caused by low levels of C15:0. Named the Cellular Fragility Syndrome, this deficiency may impact as many as one in three people worldwide. C15:0 is an odd-chain saturated fatty acid found primarily in whole-fat dairy and some types of plants and fish. Studies have shown that declining C15:0 levels are widespread across populations, primarily due to the growing trend of turning away from whole-fat dairy products. Experts say that the daily intake of cow’s milk has reduced with each generation, a practice that the US Department of Agriculture terms “difficult to reverse.”