06 Jul 2020 --- Supplementation with a combination of the curcuminoid C3 Complex and piperine BioPerine can significantly decrease pro-inflammatory cytokine leptins in critically ill patients with traumatic brain injury (TBI). This is according to a new study published in Phytotherapy Research, which demonstrated the utility of combining the curcumin brand and the bioavailability enhancer to monitor the expression of cytokines in TBI patients. Moreover, it presents a new avenue of managing brain health with curcumin.