14 Aug 2019 --- In obesity resulting from consuming a high-fat diet or overeating, the body stops responding to natural hormonal signals of satiety, or “fullness.” This mice-study finding has been coined a “new piece of the complex puzzle” of weight gain by the team at Baylor College of Medicine, Texas, US. It is widely known that leptin, a hormone produced by fat cells, triggers the sensation of feeling full when we have eaten enough. Until now, it was unknown that fatty foods could inhibit this natural process through a gut mechanism. These findings further implicate the importance of a healthy diet in weight loss and maintenance.
