12 Mar 2018 --- Following a low-fat diet in combination with limited caloric consumption can prevent age-related brain dysfunction in aging mice. The study, published in Frontiers in Molecular Neuroscience, also finds that exercise is far less effective than the caloric restriction in preventing such neurological, age-related changes. Although an early day’s rodent study, this data could demonstrate the potential importance of dietary fat intake on brain health in aging populations.